Paul Bonard an artist, loses his memory when he receives a blow on the head from one of two apaches fighting over Wildcat, a sultry stepper in a cafe. He becomes an apache himself, falls in love with Wildcat and paints her portrait-his masterpiece. Wildcat learns Paul's identity and restores him to his family, though realizing that she will lose him. Surgery restores Paul's memory, but some subconscious force guides him back to the cafe and Wildcat's love.
Unscrupulous stockbroker George Howard convinces Robert Sterling that he is having an affair with Robert’s wife Helen aided by Robert’s former flame, Rita Lawson who wants him for herself. Though Robert believes the lie, divorcing Helen and gaining custody of their child, Helen still wants nothing to do with George. Mad with desire he kidnaps her daughter and demands Helen sleep with him for the girl’s safe return. Forced into a corner, Helen agrees but once her daughter is rescued a struggle ensues with George and he is shot dead. Helen, cleared of wrongdoing reunites with Robert who has realized his folly.
Conchita Cordova sings in the cathedral choir in her village of San Miguelito near the Rio Grande. Millionaire oil man John Rannie, whose oil fields have displaced the peasants, desires Conchita, and when he learns that her fiance, Juan Mendoza, has been employed by Adolf Wylie, a German spy, Rannie threatens to expose Juan unless Conchita gives herself to him.
Serama, the consort of Lucifer, is driven from Paradise by the Archangel Michael, who commands Conscience to enter human souls to judge and punish them. In the main story, society girl Ruth Somers, a reincarnation of Serama, prepares to marry Cecil Brooke, the wealthiest man of her set. Her guardian, Dr. Norton, an incarnation of Lucifer, constantly accompanies her. Ruth is summoned to the Court of Conscience, where the witnesses, Lust, Avarice, Hate, Revenge and Vanity, testify about Ruth's history of seducing and abandoning men. This behavior resulted in the suicide of Madge, the lover of Ned Langley, whom Ruth enthralled and promised to marry, and also the deaths of two rivals for her love. Ruth is ordered back to earth to learn her sentence. When Ned interrupts the wedding, Ruth scorns him and he shoots himself. After Brooke leaves her, the Court dooms Ruth to live with the torment of remembrance. Ruth sends Norton away, and then kneels and repents.
When Bob Stratton returns from war in France, he soon discovers his ranch in the hands of a pretty girl, Mary Thorne, who explains that upon her father's death she became the sole owner. Thorne had been the executor of Stratton's will, and thinking that Bob had been killed, he had appropriated the place for himself.
Former miner Daniel Slade becomes a wealthy investor and runs for political office, ultimately becoming the governor of his state. Daniel's wife, Mary, is unable to adjust to a life in high society, often embarrassing him in the presence of his colleagues. Temptation arrives in the form of Katherine Strickland, the daughter of a prominent senator, who takes Daniel away from his old-fashioned wife. However, Daniel eventually realizes how much he loves Mary, and he returns to her.
When jealousy and envy lead Mary Vantyne to make a foolish decision and commit an impulsive act she sets off a series of events that nearly bring heartbreak to all those in her circle.
A woman writes about her sister's tragedy, vowing to help others in similar situations: Because Bettina longs to leave her country home, her loving mother sends her and her serious-minded elder sister to London, accepting their aunt's invitation to visit and allow Bettina to be introduced to society. The girls' dressmaker steals the aunt's photograph and sends it to a woman who, disguised as their aunt, leads the girls to a brothel. After the elder sister escapes, aided by her concerned male companion, she races in a cab to her aunt's home, but is frustrated in her attempt to rescue Bettina by her aunt's infirm state, the inefficiency of the police, and her own inability to remember the location of the house. She finds her cab driver, but he is drunk and soon dies in an accident. After falling ill, the sister, convinced by a dream that Bettina has died, resolves to devote her life to saving other women.
Nekhludoff, a Russian nobleman serving on a jury, discovers that the young girl on trial, Katusha, is someone he once seduced and abandoned and that he himself bears responsibility for reducing her to crime. He sets out to redeem her and himself in the process.
Faced with the tragic responsibility of choosing between the happiness of her 16-year-old daughter Pamela or saving the life of an innocent man, Marie Baudin's first impulse is to sacrifice all for her own. But she has second thoughts that bring complications to all.