A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.
Jim Harvey is hired to guard a small wagon train as it makes its way west. The train is attacked by Indians and Harvey, hoping to persuade Aguila, the chief, to call off the attack due to Harvey's having saved his son's life, leaves the train to negotiate. He is captured and the rest of the train is wiped out except for two sisters. Escaping and showing up in town later, Harvey is nearly hanged as a deserter, but gets away. Eventually caught by the sheriff and his posse, they are attacked by Indians. This time the Indians are defeated and Aguila, captured and dying, reveals the identity of the white man who engineered the initial attack on the wagon train, just as the perpetrator rides up behind them.
Convict Cheyenne Harry escapes from prison in a garbage truck and boards a train, where he eludes capture with the help of passenger Henry Beaufort. Beaufort is returning to his wealthy uncle's ranch, where earlier he had married Molly in secret because his uncle did not like her. Beaufort tells Pedro, who takes care of his child Elizabeth, to take her away because his uncle is coming, and Pedro, driving drunk, wrecks the wagon. Harry finds her and must protect her while still evading the sheriff.
Former P.O.W. Jack Calgrove moves Heaven and Earth to be reunited with his children following the Civil War. After returning home, Jack discovers that his wife has tragically died and his children, presumed to be orphans, are heading deep into the West on a train crossing enemy lines, with the intent of being placed into new homes. Calgrove and another soldier team up with a troop of Native American sharpshooters and a freed slave as they try to stop the train.
A former gunslinger is forced to take up arms again when he and his cattle crew are threatened by a corrupt lawman.
At the height of the frontier era, a train races through the Rocky Mountains on a classified mission to a remote army post. But one by one the passengers are being murdered, and their only hope is the mysterious John Deakin, who's being transported to face trial for murder.
Dan Evans, a small time farmer, is hired to escort Ben Wade, a dangerous outlaw, to Yuma. As Evans and Wade wait for the 3:10 train to Yuma, Wade's gang is racing to free him.
In 1870s America, a peaceful American settler kills his family's murderer which unleashes the fury of a notorious gang leader. His cowardly fellow townspeople then betray him, forcing him to hunt down the outlaws alone.
A Mexican bandit is about to be executed in the United States, so his brother takes over a train and holds the passengers as hostages unless his brother is released. Now both the Americans and Mexicans are baffled as to what to do. One of the passengers — who wrote the letter for their captor — has a suggestion: call mercenaries Hank Brackett and Johnny Reech. They do, and as expected they do come up with a plan, but the president of the railroad is not sure if it will work.
Daniel Bone is aiming for success. A Brooklyn gunsmith by trade, he figures the place to be is where the guns are. So off he goes into the West and becomes the foe of the notorious Pecos Kid, the captive of Paiutes, the target in a saloon showdown, and the lone source of the whereabouts of a fabulous gold strike.
As Colorado Springs' Commisioner, Sully opposes a deal to mine for copper to make electricity. In order to sway Sully's decision, Mr. Garrick threatens Sully. Sully and Michaela's daugther, Katie, is then kidnapped while the town celebrates Michaela's birthday. The search for Katie takes Sully, Micheala, and their friends on an adventure through Mexico that is filled with danger at every turn.