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U.S. Marshall John Kruger erases the identities of people enrolled in the Witness Protection Program. His current assignment is to protect Lee Cullen, who's uncovered evidence that the weapons manufacturer she works for has been selling to terrorist groups. When Kruger discovers that there's a corrupt agent within the program, he must guard his own life while trying to protect Lee's.

At the height of the frontier era, a train races through the Rocky Mountains on a classified mission to a remote army post. But one by one the passengers are being murdered, and their only hope is the mysterious John Deakin, who's being transported to face trial for murder.

A group of skiers are trapped inside a runaway train hurtling down a mountainside.

On a train headed for England a group of travelers is delayed by an avalanche. Holed up in a hotel in a fictional European country, young Iris befriends elderly Miss Froy. When the train resumes, Iris suffers a bout of unconsciousness and wakes to find the old woman has disappeared. The other passengers ominously deny Miss Froy ever existed, so Iris begins to investigate with another traveler and, as the pair sleuth, romantic sparks fly.

Sadistic killer-for-hire Philip Raven becomes enraged when his latest job is paid off in marked bills. Vowing to track down his double-crossing boss, nightclub executive Gates, Raven sits beside Gates' lovely new employee, Ellen, on a train out of town. Although Ellen is engaged to marry the police lieutenant who's hunting down Raven, she decides to try and set the misguided hit man straight as he hides from the cops and plots his revenge.

The horrors of war are examined from the view points of lifelong friends (Linus Roache, Vincent Perez), who end up on opposing sides in the civil war in Sarajevo. One is an expert marksman, who trains the snipers used to terrify the city and the other becomes a freedom fighter, who rejects his friend's offer to gain an escape from the city. As might be expected, the two eventually have to face-off against one another.

Strike is a young city drug pusher under the tutelage of drug lord Rodney Little. When a night manager at a fast-food restaurant is found with four bullets in his body, Strike’s older brother turns himself in as the killer. Detective Rocco Klein doesn’t buy the story, however, setting out to find the truth, and it seems that all the fingers point toward Strike & Rodney.

A Chinese Department of Health junior clerk Su Zhenghuai is with his eldest daughter Su Wei and son Su Yuexuan are on their way to visit relatives in the provincial city when they meet the long-lost second daughter Su Ling. Unfortunately, the train is attacked by rats. Su Yuexuan is bitten by a rat and goes into a coma. In order to save his young son and many bitten passengers, Su Zhenghuai and Su Wei decide to make the dangerous venture to Xiaobaihe Hospital to get medicine.

A quiet stroll through the imaginary world of Iblard, originally depicted in the paintings by Naohisa Inoue, influenced by Impressionism and Surrealism.

On the eve of World War II, zany heiress Amanda Kelly travels by train to Switzerland. While passing through Germany, she meets a sweet elderly lady, who suddenly vanishes. Distraught, she questions her fellow passengers who claim that the woman was never there. Unsure if it's all in her mind or if there's a more sinister plot afoot, Amanda teams up with photographer Robert Condon to discover the truth.

Six people travel by train overnight from Marseilles to Paris. When the train arrives at its destination, one of the passengers, a girl, is found dead in a sleeping berth. The police led by Inspector Grazzi investigate the other five passengers, suspecting that one of them was responsible. However, as the investigation is stepped up, the other passengers start turning up dead. It is then up to the last remaining two to solve the case, before they become the next victims.