Anna Karenina is a married aristocrat and socialite living in Saint Petersburg. She is living a torrid romance with a wealthy and young count, he loves her and is willing to marry her once she leave her husband.
Doris Poole, whose parents were theatrical people, was orphaned as a child, and four members of the troupe adopted and raised her. When grown, she has become the leading lady in a San Francisco stock-company. She meets and falls in love with Ted, the millionaire son of a rich widow, but she thinks he is only a tax-cab driver. His mother objects to the romance and looks into Doris' past. She learns that her father had murdered, in a fit of jealousy, her mother, and tells Doris what she has found out. The four actors who had raised her had never told her how she happened to become an orphan. They persuade Ted's mother to send him on a voyage to the Orient in order to get him away from Doris. But they neglected to tell the mother they had also booked passage for Doris on the same ship.
During the Easter Carnival, Dolores de Cordova flirts with Juan Estudillo, not knowing that he is a member of the family with whom her ancestors have long feuded. Dolores' cousin, Pedro Toral, jealous of her attentions to Juan, kills her brother that night and after leaving Juan's handkerchief by the body, makes Dolores swear to avenge the death with her own hands....
Lacking patients, Dr. Sumner sets himself up as a psychologist and opens a sanitarium, becoming quite successful. Virginia Zelva, a clairvoyant who wants to get into what she regards as a racket, signs on as his nurse. Sumner falls in love with Virginia and, after numerous complications, wins her for his bride.
When she is orphaned Lily Upjohn, from the London slums, becomes a chorus girl at the Pandora Theatre. During a performance a scene painter drops some paint near Lily and her screams prompt the show's composer to create a hit song "Mind the Paint Girl," which Lily makes an overnight sensation. She is courted by young officer Nicholas Jeyes and by Lord Francombe. Driving both men to near ruin she promises marriage to both but in the end choses neither.
When her cotton crop is burned, Barbara Pelham, a beautiful southern girl, comes to New York to find work as a fashion designer, staying with Mrs. Kemp, a woman she meets on the northbound train. In Mrs. Kemp's house, Barbara encounters Peter Heffner, a wealthy stockbroker, and discovers from him that she has taken up residence in a whorehouse. There is a police raid, but Barbara escapes arrest and returns home. Heffner's son, Neil, goes south to inspect some family property and there meets Barbara, with whom he falls in love. They decide to be married, and she accompanies him to New York, where she meets the elder Heffner for a second time. He denounces her as a whore, but Barbara goes to Mrs. Kemp, who explains the misunderstanding to everyone's satisfaction.
Unscrupulous politician Mark Stetson frames Mr. & Mrs. Brandon and their friend Antoinette for a smuggling racket he runs. Upon their release they swear vengeance and after Stetson once again tries to incriminate them, this time in a plot against a rival politician, justice is theirs.
When burlesque dancer Elois Murree gives birth to her daughter Yvette, she sends to a fashionable boarding school away from the stage environment and her drunken husband. Yvette visits infrequently but during one sojourn Murree slashes Elois' left eye in an argument forcing Elois, now veiled, to perform billed as the Masked Queen. Yvette becomes attracted to her friend’s brother, Rex, she avoids him after she learns that he wants his prospective bride to come from a good family. Yvette becomes a burlesque queen, but a distraught Elois tries to kill her to save her soul and then commits suicide, leaving the bloodied knife in the hands of her drunken husband, who then is arrested. Later, Yvette finds happiness with Rex.
A chorus girl breaks a deal with her boss by marrying the rich man she was supposed to ruin.
American author John B. Smart, searching for solitude and an atmosphere for a new story, purchases an old castle in Switzerland. He discovers the beautiful Aline hiding with a baby in the east tower. Daughter of an American millionaire she on running from her ex-husband Count Tarnowsky, who squandered her money and treated her brutally, but whom the courts have awarded their child. The Count arrives confronting John who overcomes him and has him thrown into the dungeon. Smart, Aline and her child flee on a sleigh speeding towards the Italian border with the escaped Count in pursuit. In the nick of time they safely cross the border and Aline consents to be John's wife.
Madame Vavin dies alone in a small French village without knowledge of her second marriage in England known to anyone. Consequentially her first husband James Fullerton and his tyrannical sister Cornelia take custody of her young daughter Dora. The puritanical pair take Dora to America but disapprove of her spirited nature especially when Dora decides upon a theatrical career. On stage, Dora meets and falls in love with playwright Willard Holcomb, but the fears implanted by Fullerton and his sister make Dora incapable of romantic commitment. As she despairs of her fate, Professor Vavin, who has spent years searching for Dora, discovers his daughter and explains there is nothing to fear from love. Her confidence thus restored, Dora can continue with her life.