The story of a boy, a dog, and a man. The boy discovers he is heir to a shipping line, and travels to Los Angeles, accompanied by inventor/radio operator Bob Whitlock and Irene Blaine. Their journey is aided by Pal, a wolf dog.
Sergeant MacLane of the Mounties investigates the disruptive activities of a bunch of troublemakers.
The nefarious Dr. Fu Manchu searches for the keys to the tomb of Genghis Khan, in order to fulfill a prophecy that will enable him to conquer the world. His nemesi, Dr. Nayland Smith and his associates fight to keep the evil doctor from getting his hands on the keys. In 1943 the serial was edited together into a feature movie also called Drums of Fu Manchu.
A Secret Service agent seeks his missing brother in Africa, and finds his mission complicated by ivory thieves, a girl with a mysterious past, and a troublesome gorilla.
A new town doctor arrives at the same time as local Indians needprotection from troublemaking looters.
An Indian rug is the key to the location of a lost treasure. When the rug's owner is murdered, it becomes a case for Forest Ranger Steve King
Calvin Drake employs a group of low-lifes to drive away land owners along the path of a new railroad; Red Ryder opposes this strategy.
Tom King Jr. seeks to discover who murdered his father, a Texas Ranger; the trail leads to a network of Axis spies.
Jesse James wants to start a new life in a new location, but quickly finds himself wrapped-up in protecting townsfolk from the machinations of evil oilmen.