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A simple-minded gardener named Chance has spent all his life in the Washington D.C. house of an old man. When the man dies, Chance is put out on the street with no knowledge of the world except what he has learned from television.

When Maggie's sister Jenna saddles her with an autistic newborn named Cody she touches Maggie's heart and becomes the daughter she has always longed for. But six years later Jenna suddenly re-enters her life and, with her mysterious new husband, Eric Stark, abducts Cody. Despite the fact that Maggie has no legal rights to Cody, FBI agent John Travis takes up her cause when he realizes that Cody shares the same birth date as several other recently murdered children.

Jake, a high schooler on the autistic spectrum, feels disillusioned with the world. When he meets Alice, he begins to experience the world in other ways. Little does Jake know, Alice may have more in common with him than he could imagine.

In a remote woodland cabin, a small town doctor discovers Nell — a beautiful young hermit woman with many secrets.

A man with a low IQ has accomplished great things in his life and been present during significant historic events—in each case, far exceeding what anyone imagined he could do. But despite all he has achieved, his one true love eludes him.

Harassed by bullies because of his mild autism, teen Ben finds refuge in an online computer game, which leads him to his virtual dream girl, Scarlite. Together, the odd couple seeks revenge against Ben's tormentors.

A mentally ill young woman finds her love in an eccentric man who models himself after Buster Keaton.

Renegade FBI agent Art Jeffries protects a nine-year-old autistic boy who has cracked the government's new "unbreakable" code.

Thomas is turning 16. His dad's in the army and they've just moved to a town in New South Wales; his mom is pregnant; his older brother, Charlie, who's autistic, has his own adolescent sexual issues. Thomas finds Charlie an embarrassment in public, so when Thomas is attracted to Jackie, a girl in his swim class, Charlie presents any number of obstacles when she drops by their house, when the three of them go for a walk, and during a family birthday dinner. Can Thomas find a way to enter the world of teen romance and still be his brother's keeper, or is Charlie's disability going to prove more than Thomas can handle?

A drama focused on the friendship between a high-functioning autistic woman and a man who is traumatized after a fatal car accident.

When car dealer Charlie Babbitt learns that his estranged father has died, he returns home to Cincinnati, where he discovers that he has a savant older brother named Raymond and that his father's $3 million fortune is being left to the mental institution in which Raymond lives. Motivated by his father's money, Charlie checks Raymond out of the facility in order to return with him to Los Angeles. The brothers' cross-country trip ends up changing both their lives.