A gunslinger returns to his hometown to warn of an impending outlaw gang attack, but he's met with hatred and fear for his previous killings.
Wealthy rancher Bick Benedict and dirt-poor cowboy Jett Rink both woo Leslie Lynnton, a beautiful young woman from Maryland who is new to Texas. She marries Benedict, but she is shocked by the racial bigotry of the White Texans against the local people of Mexican descent. Rink discovers oil on a small plot of land, and while he uses his vast, new wealth to buy all the land surrounding the Benedict ranch, the Benedict's disagreement over prejudice fuels conflict that runs across generations.
Jim Killian arrives in a small Arizona town hoping to establish a peaceful life as the local preacher, but he soon finds himself in the middle of a feud between sheep ranchers and cattlemen. Leloopa, a young Native American woman, pleads for Killian's help after her shepherd father is hung by Coke Beck, the vicious son of the head cattle rancher. Killian must weigh his actions carefully lest he perpetuate the cycle of retribution and revenge.
In early 20th-century Montana, Col. William Ludlow lives on a ranch in the wilderness with his sons, Alfred, Tristan, and Samuel. Eventually, the unconventional but close-knit family are bound by loyalty, tested by war, and torn apart by love, as told over the course of several decades in this epic saga.
Singing cowboy Whip Wilson, the foreman on a cattle drive, quits his job to pursue five bank robbers who murdered his brother.
Rodeo contestants Johnny King and Corrigan meet, their fathers having been members of the Range Busters. When Johnny is knocked unconscious, time reverts to their father's era and the Range Busters are soon involved in the scheme to get Railroad right-of-way across Mother Slocum's ranch. When she is tricked into signing a release, the Range Busters find their job more difficult as the Sheriff is in with the crooks.
An aging group of outlaws look for one last big score as the "traditional" American West is disappearing around them.
Banker Mason is after the ranchers land so he can resell it to the railroad for a profit. He has the railroad agent killed and replaces him with his stooge who then offers even less than Mason. But Rocky eventually suspects Mason and when Bill Anderson informs him the agent is a fake, they head out after Mason
Outlaws plan a robbery to take place during a championship prizefight in Carson City, Nevada.
Carl Beldon has disappeared and the Trail Blazers have been sent to investigate. Arriving in town, they find that 'Honest John' controls everything. He even prints his own money. He also has a gang and they set out to finish off the heroes.
In Arizona in the late 1800s, infamous outlaw Ben Wade and his vicious gang of thieves and murderers have plagued the Southern Railroad. When Wade is captured, Civil War veteran Dan Evans, struggling to survive on his drought-plagued ranch, volunteers to deliver him alive to the "3:10 to Yuma", a train that will take the killer to trial.