Nacho Libre is loosely based on the story of Fray Tormenta ("Friar Storm"), aka Rev. Sergio Gutierrez Benitez, a real-life Mexican Catholic priest who had a 23-year career as a masked luchador. He competed in order to support the orphanage he directed.
Real-life clown Jack Thum, along with his devoted wife, Shirlee, cared for dozens of homeless children — 37 of them over the years — in the Chicago area, all of whom come back to visit when they discover he's terminally ill.
Lyla and Louis, a singer and a musician, fall in love, but are soon compelled to separate. Lyla is forced to give up her newborn but unknown to her, he grows up to become a musical genius.
During the Vietnam War, Brian Anderson, a young Army medic, is stationed in Saigon. Initially apathetic and self-serving, he eventually has his heart won over by the children at a nearby orphanage where he does volunteer work. At first, a doctor named Katherine Cross has to persuade him to help the children. But soon, Brian willingly puts his career and safety on the line to provide the orphans with the food and medical supplies they need.
After a socially conscience reporter adopts a slum orphan after she causes his brother's gang to go to prison.
A sensitive girl is sent to an all-girls boarding school and develops a romantic attachment to one of her teachers.
For many years, four teenage orphans at an Australian outback convent have watched their younger comrades find new parents, and realize that they may never be adopted. The Reverend Mother sends the four boys away on a seaside vacation, where they meet Teresa and Fearless, a couple who would make perfect parents. The youths compete with one another to be the one Teresa and Fearless decide to adopt.
A young boy and his family set off on a sailing trip of a lifetime until a violent storm erupts, sweeping Michael and his dog overboard. After washing up on a remote island, terrified, they struggle to survive and adjust to life alone, One day, Michael discovers he is not alone when he is confronted by a mysterious Japanese man who has lived there secretly since World War II, angry that Michael has arrived. However, as dangerous invaders threaten their fragile island paradise, Michael and the old man, Kensuke, join forces to save their secret world.
A minister and his wife take in poor and troubled children that nobody else wants and soon they find themselves with a family of a dozen kids.
Lah is a mahout who works his elephant at an illegal logging site in Burma. When they're about to get busted, he sends his son Saeng and his elephant to relatives in Bangkok. Saeng ends up begging the streets of Bangkok with his elephant and he comes in contact with the local mafia who wants their cut or else.